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Magnesium L-Threonate Half-Life & Clearance
Understand how long Magnesium L-Threonate stays in your bloodstream, its metabolic pathways, and how to time your doses optimally.
Standard Pharmacokinetics
Chart represents a single standard dose processed by a normal metabolizer over 24 hours.
Key Metrics
8 hrs
Average Half-Life
+2.5 hrs
Time to Peak (Tmax)
Take with food to reduce GI discomfort
Food interaction
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See how Magnesium L-Threonate overlaps with caffeine, modafinil, and your target bedtime.
Open Interactive CalculatorMetabolism & Excretion
Pathway
Intestinal absorption; crosses blood-brain barrier more effectively than other magnesium forms
Elimination
Urine
Important Nuances
MgT (Magtein) is unique in its ability to increase brain magnesium levels. Requires consistent supplementation for 4–6 weeks to significantly increase cerebrospinal fluid magnesium. Most research uses 1.5–2g MgT (providing ~144mg elemental magnesium).
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